Have you ever hit ⌘T and had the worthless "Fonts" dialog popup instead of what you intended to happen? To me "T" means "Tab" or "tags" depending on the application.
One example where I wanted "tags" instead of looking at the above dialog, is Evernote. So finally being fed up with the expected result of what ⌘T should do and what it was doing by default, I edited the keyboard shortcut.
This tip works across all OSX applications and it can really help out when an application doesn't allow a shortcut to be defined.
Go into "Preferences" then "Keyboard". At the top, click "Shortcuts". On the left side, click "App Shortcuts". Then click the "+" at the bottom of the right pane and add something that looks like this:
One caveat here is that you must match the menu command exactly as it appears in the application. If it is a subcommand, you just enter the menu item (i.e. no prefixes are needed if it's in "Edit > Styles").